The Journal of Arthroplasty
Volume 19, Issue 4, Supplement 1 , Pages 69-72, June 2004

Prophylactic use of antibiotic bone cement:

an emerging standard—in the affirmative1

  • Robert B Bourne, MD (FRCSC)

      Affiliations

    • London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    • Corresponding Author InformationReprint requests: Dr. R. B. Bourne, London Health Sciences Centre, 339 Windermere Road, London, Ontario, N6A 5A5, Canada

Abstract 

Deep infection is a devastating complication following total joint arthroplasty. Preclinical testing; randomized; clinical trials; national joint replacement data; and our experience indicate that the use of antibiotic-impregnated bone cement is a potentially effective strategy in reducing the risk of deep infection following both primary and revision total joint arthroplasty. Allergic reactions, bacterial resistance, and cost represent barriers to the widespread use of antibiotic bone cement.

Keywords:  prophylactic, antibiotic, bone cement

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  • 1 No benefits or funds were received in support of this study.

PII: S0883-5403(04)00211-6

doi:10.1016/j.arth.2004.03.005

The Journal of Arthroplasty
Volume 19, Issue 4, Supplement 1 , Pages 69-72, June 2004

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