The Journal of Arthroplasty
Volume 23, Issue 1 , Pages 90-96 , January 2008

Symptomatic Osteonecrosis of the Hip and Knee After Cardiac Transplantation

  • Jay R. Lieberman, MD

      Affiliations

    • The Musculoskeletal Institute and the Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, Connecticut
    • Corresponding Author InformationReprint requests: Jay R. Lieberman, MD, The New England Musculoskeletal Institute and the Department of Orthopaedic Surgery, University of Connecticut Health Center, Medical Arts and Research Building, 263 Farmington Ave, Farmington, CT 06030-5456.
    • ,
  • Kevin M. Roth, BA

      Affiliations

    • Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California
    • ,
  • Peter Elsissy, MD

      Affiliations

    • Department of Orthopaedic Surgery, Loma Linda University Medical Center, Loma Linda, California
    • ,
  • Frederick J. Dorey, PhD

      Affiliations

    • Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, California
    • ,
  • Jon A. Kobashigawa, MD

      Affiliations

    • Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California

Received 9 July 2006 ,Accepted 8 January 2007.

References 

  1. Parfrey PS, Farge D, Parfrey NA, et al. The decreased incidence of aseptic necrosis in renal transplant recipients—a case control study. Transplantation. 1986;41:2
  2. Felson DT, Anderson JJ. Across-study evaluation of association between steroid dose and bolus steroids and avascular necrosis of bone. Lancet. 1987;1:8538
  3. Lopez-Ben R, Mikuls TR, Moore DS, et al. Incidence of hip osteonecrosis among renal transplantation recipients: a prospective study. Clin Radiol. 2004;59:5
  4. Abbott KC. Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States. Transplantation. 2005;79:3
  5. Inoue S. Risk factors for nontraumatic osteonecrosis of the femoral head after renal transplantation. J Orthop Sci. 2003;8:6
  6. Papagelopoulos PJ. Total joint arthroplasty in orthotopic liver transplant recipients. J Arthroplasty. 1996;11:8
  7. Lieberman JR, Scaduto AA, Wellmeyer E. Symptomatic osteonecrosis of the hip after orthotopic liver transplantation. J Arthroplasty. 2000;15:6
  8. Bradbury G, Benjamin J, Thompson J. Avascular necrosis of bone after cardiac transplantation. Prevalence and relationship to administration and dosage of steroids. J Bone Joint Surg Am. 1994;76:9
  9. Taylor AL. Immunosuppressive agents in solid organ transplantation: mechanisms of action and therapeutic efficacy. Crit Rev Oncol Hematol. 2005;56:1
  10. Morrow SA. The bioavailability of IV methylprednisolone and oral prednisone in multiple sclerosis. Neurology. 2004;63:6
  11. Monegal A. Bone mass and mineral metabolism in liver transplant patients treated with FK506 or cyclosporine A. Calcif Tissue Int. 2001;68:2
  12. Danzig LA, Coutis RD, Resnick D. Avascular necrosis of the femoral head following cardiac transplantation: report of a case. Clin Orthop Relat Res. 1976;117:117
  13. Nishiyama K, Okinaga A. Osteonecrosis after renal transplantation in children. Clin Orthop Relat Res. 1993;295:295
  14. Susan LP, Brown WE, Banowsky LH, et al. Avascular necrosis following renal transplantation. Experience with 449 allografts with and without high-dose steroid therapy. Urology. 1978;11:3
  15. Elmstedt E. Avascular bone necrosis in the renal transplant patient: a discriminant analysis of 144 cases. Clin Orthop Relat Res. 1981;158:158
  16. Lieberman JR, Berry DJ, Mont MA, et al. Osteonecrosis of the hip: management in the 21st century. Instr Course Lect. 2003;52:337
  17. Asano T, Takahashi KA, Fujioka M, et al. ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation. Pharmacogenetics. 2003;13:11
  18. Marston SB, Gillingham K, Bailey RF, et al. Osteonecrosis of the femoral head after solid organ transplantation: a prospective study. J Bone Joint Surg Am. 2002;84-A:12
  19. Hernigou P. Fate of very small asymptomatic stage-I osteonecrotic lesions of the hip. J Bone Joint Surg Am. 2004;86-A:12

 No benefits or funds were received in support of the study.

PII: S0883-5403(07)00045-9

doi: 10.1016/j.arth.2007.01.006

The Journal of Arthroplasty
Volume 23, Issue 1 , Pages 90-96 , January 2008

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