The Journal of Arthroplasty
Volume 23, Issue 7 , Pages 1080-1085 , October 2008

Metal Sensitivity as a Cause of Groin Pain in Metal-on-Metal Hip Resurfacing

  • Pat Campbell, PhD

      Affiliations

    • JVL Orthopaedic Research Center, Orthopaedic Hospital, UCLA Department of Orthopaedics, Los Angeles, California
    • Corresponding Author InformationReprint requests: Pat Campbell, PhD, Orthopaedic Hospital, 2400 S. Flower St., Los Angeles, CA 90007.
    • ,
  • Andrew Shimmin, MD

      Affiliations

    • Melbourne Orthopaedic Group, Melbourne, Australia
    • ,
  • Len Walter, MD

      Affiliations

    • Peninsula Orthopaedics, Sydney, Australia
    • ,
  • Michael Solomon, MD

      Affiliations

    • Prince of Wales Hospital, Sydney, Australia

Received 20 March 2007 ,Accepted 28 September 2007.

References 

  1. Benson MK, Goodwin PG, Brostoff J. Metal sensitivity in patients with joint replacement arthroplasties. Br Med J. 1975;4:374
  2. Evans EM, Freeman MAR, Miller AJ, et al. Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement. J Bone Joint Surg. 1974;56B:626
  3. Deutman R, Mulder TH, Brian R, et al. Metal sensitivity before and after total hip arthroplasty. J Bone Joint Surg. 1977;59A:862
  4. Willert HG, Buchhorn GH, Fayazi A, et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg. 2005;87A:28
  5. Willert HG, Buchorn G, Fayyazi A, et al. Histopathological changes around metal/metal joints indicate delayed type hypersensitivity. Preliminary results of 14 cases. Osteologie. 2000;9:2
  6. Park YS, Moon YW, Lim SJ, et al. Early osteolysis following second-generation metal-on-metal hip replacement. J Bone Joint Surg. 2005;87A:1515
  7. Milosev I, Trebse R, Kovac S, et al. Survivorship and retrieval analysis of Sikomet metal-on-metal total hip replacements at a mean of seven years. J Bone Joint Surg. 2006;88B:1173
  8. Korovessis P, Petsinis G, Repanti M, et al. Metallosis after contemporary metal-on-metal total hip arthroplasty. Five to nine-year follow-up. J Bone Joint Surg. 2006;88A:1183
  9. Davies A, Willert HG, Campbell PA, et al. An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg. 2005;87B:18
  10. Al-Saffar N. Early clinical failure of total joint replacement in association with follicular proliferation of b-lymphocytes: A report of two cases. J Bone Joint Surg. 2002;84A:2270
  11. Shahrdar C, Campbell P, Mirra J, et al. Painful metal-on-metal total hip arthroplasty. J Arthroplasty. 2006;21:289
  12. Hallab N, Merritt K, Jacobs JJ. Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg. 2001;83A:428
  13. Jacobs JJ, Skipor AK, Campbell PA, et al. Can metal levels be used to monitor metal-on-metal hip arthroplasties?. J Arthroplasty. 2004;19:59
  14. Hallab NJ, Mikecz K, Jacobs JJ. A triple assay technique for the evaluation of metal-induced, delayed-type hypersensitivity responses in patients with or receiving total joint arthroplasty. J Biomed Mater Res. 2000;53:480
  15. Hallab N, Anderson S, Caicedo M, et al. Immune responses correlate with serum-metal in metal-on-metal hip arthroplasty. J Arthroplasty. 2004;19:88

 William G. McGowan Research Foundation and the Los Angeles Orthopaedic Hospital Foundation provided funding for this study.

PII: S0883-5403(07)00593-1

doi: 10.1016/j.arth.2007.09.024

The Journal of Arthroplasty
Volume 23, Issue 7 , Pages 1080-1085 , October 2008

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