The Journal of Arthroplasty
Volume 23, Issue 8 , Pages 1232-1238 , December 2008

Biological and Biomechanical Effects of Vancomycin and Meropenem in Acrylic Bone Cement

  • Massimiliano Baleani, MSc

      Affiliations

    • Laboratorio di Tecnologia Medica, Istituti Ortopedici Rizzoli, Bologna, Italy
    • Corresponding Author InformationReprint requests: Massimiliano Baleani, MSc, Laboratorio di Tecnologia Medica, Istituti Ortopedici Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
    • ,
  • Cecilia Persson, MSc

      Affiliations

    • Laboratorio di Tecnologia Medica, Istituti Ortopedici Rizzoli, Bologna, Italy
    • ,
  • Carola Zolezzi, MSc

      Affiliations

    • Banca del Tessuto Muscolo-Scheletrico, Istituti Ortopedici Rizzoli, Bologna, Italy
    • ,
  • Agnese Andollina, MD

      Affiliations

    • Laboratorio di Patologia Clinica, Istituti Ortopedici Rizzoli, Bologna, Italy
    • ,
  • Anna Maria Borrelli, MD

      Affiliations

    • CIO Direzione Sanitaria, Istituti Ortopedici Rizzoli, Bologna, Italy
    • ,
  • Domenico Tigani, MD

      Affiliations

    • VII Divisione di Chirurgia Ortopedico-traumatologica, Istituti Ortopedici Rizzoli, Bologna, Italy

Received 21 March 2006 ,Accepted 8 October 2007.

References 

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  19. Chohfi M, Langlais F, Fourastier J, et al. Pharmacokinetics, uses, and limitations of vancomycin-loaded bone cement. Int Orthop. 1998;22:3
  20. Hanssen AD. Prophylactic use of antibiotic bone cement: an emerging standard—in opposition. J Arthroplasty. 2004;19(4 Suppl 1):73
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  22. Kelm J, Regitz T, Schmitt E, et al. In vivo and in vitro studies of antibiotic release from and bacterial growth inhibition by antibiotic-impregnated polymethylmethacrylate hip spacers. Antimicrob Agents Chemother. 2006;50:1
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 Tecres Spa, Verona, Italy, provided the bone cement necessary for the study.

PII: S0883-5403(07)00605-5

doi: 10.1016/j.arth.2007.10.010

The Journal of Arthroplasty
Volume 23, Issue 8 , Pages 1232-1238 , December 2008

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