The Journal of Arthroplasty
Volume 26, Issue 6, Supplement , Pages 19-23, September 2011

Gender is a Significant Factor for Failure of Metal-on-Metal Total Hip Arthroplasty

  • Michael J. Latteier, MD

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio
    • ,
  • Keith R. Berend, MD

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio
    • Mount Carmel Health System, Columbus, Ohio
    • The Ohio State University, Columbus, Ohio
    • Corresponding Author InformationReprint requests: Keith R. Berend, MD, FACS, Joint Implant Surgeons, Inc., 7277 Smith's Mill Road, Suite 200, New Albany, Ohio 43054.
    • ,
  • Adolph V. Lombardi Jr., MD, FACS

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio
    • Mount Carmel Health System, Columbus, Ohio
    • The Ohio State University, Columbus, Ohio
    • ,
  • Andrew F. Ajluni, DO

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio
    • ,
  • Brian E. Seng, DO

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio
    • ,
  • Joanne B. Adams, BFA

      Affiliations

    • Joint Implant Surgeons, Inc., New Albany, Ohio

Received 16 September 2010; accepted 4 April 2011. published online 06 June 2011.

Abstract 

Metal-on-metal (MoM) articulations offers low wear, larger head size, and increased stability. Reports of early failure are troubling and include failure of ingrowth and metal articulation problems such as metallosis, hypersensitivity, pseudotumor, and unexplained pain. This study investigates the survivorship of modern MoM articulations by gender. We reviewed 1589 primary MoM THA in 1363 patients, with minimum 2-year follow-up for 1212 hips. Follow-up averaged 60 months. There were 643 female patients and 719 male patients. The incidence of cup revision was significantly higher in women than in men (8.2% vs 2.7%; P = .0000), as was incidence of aseptic loosening (4.3% vs 1.1%; P = .0006), and failure for metal-bearing complications (2.2% vs 0.6%; P = .0126). There appear to be gender factors influencing the success of MoM THA, which may include hormonal, anatomic, or functional differences.

Keywords: total hip arthroplasty, metal-on-metal, pseudotumor, hypersensitivity, gender difference

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 The Conflict of Interest associated with this study can be found at doi:10.1016/j.arth.2011.04.012.

PII: S0883-5403(11)00171-9

doi:10.1016/j.arth.2011.04.012

The Journal of Arthroplasty
Volume 26, Issue 6, Supplement , Pages 19-23, September 2011

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