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Low Rates of Heterotopic Ossification After Resurfacing Hip Arthroplasty With Use of Prophylactic Radiotherapy in Select Patients

  • Tim J. Kruser, MD

      Affiliations

    • Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • Corresponding Author InformationReprint requests: Tim J. Kruser, MD, K4/B100 CSC, 600 Highland Ave, Madison, WI 53792.
    • ,
  • Kevin R. Kozak, MD, PhD

      Affiliations

    • Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • ,
  • Donald M. Cannon, MD

      Affiliations

    • Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • ,
  • Christopher S. Platta, MD

      Affiliations

    • Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • ,
  • John P. Heiner, MD

      Affiliations

    • Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
    • ,
  • Richard L. Illgen II, MD

      Affiliations

    • Department of Orthopedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin

Received 19 July 2011; accepted 11 November 2011. published online 16 January 2012.
Corrected Proof

Abstract 

Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.

Keywords: surface replacement arthroplasty, heterotopic ossification, prophylactic radiation

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 The Conflict of Interest statement associated with this article can be found at doi:10.1016/j.arth.2011.11.017.

PII: S0883-5403(11)00653-X

doi:10.1016/j.arth.2011.11.017

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