Abstract
We assessed important patient risk factors for postoperative periprosthetic fractures
after revision total hip arthroplasty (THA) using prospectively collected Institutional
Joint Registry data. We used univariate and multivariable-adjusted Cox regression
analyses. There were 330 postoperative periprosthetic fractures after 6281 revision
THAs. In multivariable-adjusted analyses, hazard ratio (95% confidence interval) of
periprosthetic fracture was higher for women (1.66 [1.32-2.080], P < .001), a higher Deyo-Charlson comorbidity index of 2 (1.46 [1.03-2.07]) and index
of 3+ (2.01 [1.48-2.73]; overall, P < .001), and operative diagnosis, especially previous nonunion (5.76 [2.55-13.02];
overall, P < .001). Hazard ratio was lower in patients 61 to 70 years old (0.64 [0.49-0.84])
and 71 to 80 years old (0.57 [0.43-0.76]) compared with those younger than 60 years
(overall, P < .0001). Our study identified important modifiable and unmodifiable risk factors
for fractures after revision THA.
Keywords
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Article info
Publication history
Published online: February 17, 2012
Accepted:
December 10,
2011
Received:
June 20,
2011
Footnotes
The Conflict of Interest statement associated with this article can be found at doi:10.1016/j.arth.2011.12.010.
This material is the result of work supported with the National Institutes of Health Clinical Translational Science Award 1 KL2 RR024151-01 (Mayo Clinic Center for Clinical and Translational Research) and the resources and the use of facilities at the Birmingham VA Medical Center, Birmingham, Ala.
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Copyright
Published by Elsevier Inc.
