Advertisement
Research Article| Volume 30, ISSUE 10, P1781-1786, October 2015

Serum Metal Ions with a Titanium Modular Neck Total Hip Replacement System

      Abstract

      The goal of this study is to evaluate serum levels of chromium (Cr), cobalt (Co), and titanium (Ti) within the first two years following total hip arthroplasty using a Ti modular neck system. Twenty-five patients were randomized to a metal-on-metal (MoM) bearing with an all CoCr shell, and the remaining 25 received a metal-on-polyethylene (MoP) with a Ti shell. Serum levels demonstrated increases for Cr, Co, and Ti at 1 year (P < .001). MoM had similar Ti levels to MoP hips at 1 year (P = 0.11) but lower at 2 years (P = 0.03). Results suggest that the passive corrosion (i.e., chemical, pitting, and crevice corrosion) of exposed non-articular metal surfaces may be a greater source of ions than the neck-stem or head-neck interfaces.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The Journal of Arthroplasty
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Archibeck M.J.
        • Cummins T.
        • Carothers J.
        • et al.
        A comparison of two implant systems in restoration of hip geometry in arthroplasty.
        Clin Orthop Relat Res. 2011; 469: 443
        • Traina F.
        • De Clerico M.
        • Biondi F.
        • et al.
        Sex differences in hip morphology: is stem modularity effective for total hip replacement?.
        J Bone Joint Surg. 2009; 91: 121
        • Sakai T.
        • Ohzono K.
        • Nishii T.
        • et al.
        Modular acetabular reconstructive cup in acetabular revision total hip arthroplasty at a minimum ten year follow-up.
        Int Orthop. 2013; 37: 605
        • Widmer K.-H.
        • Majewski M.
        The impact of the CCD-angle on range of motion and cup positioning in total hip arthroplasty.
        Clin Biomech (Bristol, Avon). 2005; 20: 723
        • Martin A.
        • Sheinkop M.B.
        • Langhenry M.M.
        • et al.
        Comparison of two minimally invasive implantation instrument-sets for total knee arthroplasty.
        Knee Surg Sports Traumatol Arthrosc. 2010; 18: 359
        • Malik A.
        • Maheshwari A.
        • Dorr L.D.
        Impingement with total hip replacement.
        J Bone Joint Surg Am. 2007; 89: 1832
        • Urish K.L.
        • Anderson P.A.
        • Mihalko W.M.
        The challenge of corrosion in prthopaedic implants.
        ([n.d.])
        • Vendittoli P.-A.
        • Roy A.
        • Mottard S.
        • et al.
        Metal ion release from bearing wear and corrosion with 28 mm and large-diameter metal-on-metal bearing articulations: a follow-up study.
        J Bone Joint Surg (Br). 2010; 92: 12
        • Kretzer J.P.
        • Jakubowitz E.
        • Krachler M.
        • et al.
        Metal release and corrosion effects of modular neck total hip arthroplasty.
        Int Orthop. 2009; 33: 1531
        • Kop A.M.
        • Swarts E.
        Corrosion of a hip stem with a modular neck taper junction: a retrieval study of 16 cases.
        J Arthroplasty. 2009; 24: 1019
        • Kop A.M.
        • Keogh C.
        • Swarts E.
        Proximal component modularity in THA–at what cost? An implant retrieval study.
        Clin Orthop Relat Res. 2012; 470: 1885
        • Bobyn J.D.
        • Tanzer M.
        • Krygier J.J.
        • et al.
        Concerns with modularity in total hip arthroplasty.
        Clin Orthop Relat Res. 1994; : 27
        • Pandit H.
        • Glyn-Jones S.
        • McLardy-Smith P.
        • et al.
        Pseudotumours associated with metal-on-metal hip resurfacings.
        J Bone Joint Surg (Br). 2008; 90: 847
        • Clarke M.T.
        • Lee P.T.H.
        • Arora A.
        • et al.
        Levels of metal ions after small- and large-diameter metal-on-metal hip arthroplasty.
        J Bone Joint Surg (Br). 2003; 85: 913
        • Cooper H.J.
        • Valle Della C.J.
        • Berger R.A.
        • et al.
        Corrosion at the head-neck taper as a cause for adverse local tissue reactions after total hip arthroplasty.
        J Bone Joint Surg. 2012; 94: 1655
        • Cooper H.J.
        • Urban R.M.
        • Wixson R.L.
        • et al.
        Adverse local tissue reaction arising from corrosion at the femoral neck-body junction in a dual-taper stem with a cobalt-chromium modular neck.
        J Bone Joint Surg. 2013; 95: 865
        • Wilson D.A.J.
        • Dunbar M.J.
        • Amirault J.D.
        • et al.
        Early failure of a modular femoral neck total hip arthroplasty component: a case report.
        J Bone Joint Surg. 2010; 92: 1514
        • Wright G.
        • Sporer S.
        • Urban R.
        • et al.
        Fracture of a modular femoral neck after total hip arthroplasty: a case report.
        J Bone Joint Surg. 2010; 92: 1518
        • Dangles C.J.
        • Altstetter C.J.
        Failure of the modular neck in a total hip arthroplasty.
        J Arthroplasty. 2010; 25: 1169.e5
        • Jauch S.Y.
        • Huber G.
        • Sellenschloh K.
        • et al.
        Micromotions at the taper interface between stem and neck adapter of a bimodular hip prosthesis during activities of daily living.
        J Orthop Res. 2013; 31: 1165
        • Jauch S.Y.
        • Huber G.
        • Haschke H.
        • et al.
        Design parameters and the material coupling are decisive for the micromotion magnitude at the stem-neck interface of bi-modular hip implants.
        Med Eng Phys. 2014; 36: 300
        • Omlor G.W.
        • Kretzer J.P.
        • Reinders J.
        • et al.
        In vivo serum titanium ion levels following modular neck total hip arthroplasty – 10 year results in 67 patients.
        Acta Biomater. 2013; 9: 6278
        • Gauthier L.
        • Dinh L.
        • Beaule P.E.
        Peri-acetabular bone mineral densityin total hip replacement.
        Bone Joint Res. 2013; 2: 140
        • Kim P.R.
        • Beaulé P.E.
        • Dunbar M.
        • et al.
        Cobalt and chromium levels in blood and urine following hip resurfacing arthroplasty with the Conserve Plus implant.
        J Bone Joint Surg. 2011; 93: 107
        • Jacobs J.J.
        • Cooper H.J.
        • Urban R.M.
        • et al.
        What do we know about taper corrosion in total hip arthroplasty?.
        J Arthroplasty. 2014; 29: 668
        • Brånemark P.I.
        • Adell R.
        • Albrektsson T.
        • et al.
        An experimental and clinical study of osseointegrated implants penetrating the nasal cavity and maxillary sinus.
        J Oral Maxillofac Surg. 1984; 42: 497
        • Richardson T.D.
        • Pineda S.J.
        • Strenge K.B.
        • et al.
        Serum titanium levels after instrumented spinal arthrodesis.
        Spine. 2008; 33: 792
        • McGarry S.
        • Morgan S.J.
        • Grosskreuz R.M.
        • et al.
        Serum titanium levels in individuals undergoing intramedullary femoral nailing with a titanium implant.
        J Trauma. 2008; 64: 430
        • Savarino L.
        • Padovani G.
        • Ferretti M.
        • et al.
        Serum ion levels after ceramic-on-ceramic and metal-on-metal total hip arthroplasty: 8-year minimum follow-up.
        J Orthop Res. 2008; 26: 1569
        • Savarino L.
        • Greco M.
        • Cenni E.
        • et al.
        Differences in ion release after ceramic-on-ceramic and metal-on-metal total hip replacement. Medium-term follow-up.
        J Bone Joint Surg (Br). 2006; 88: 472
        • Levine B.R.
        • Hsu A.R.
        • Skipor A.K.
        • et al.
        Ten-year outcome of serum metal ion levels after primary total hip arthroplasty: a concise follow-up of a previous report*.
        J Bone Joint Surg. 2013; 95: 512
        • Vendittoli P.-A.
        • Amzica T.
        • Roy A.G.
        • et al.
        Metal Ion release with large-diameter metal-on-metal hip arthroplasty.
        J Arthroplasty. 2011; 26: 282
        • Hexter A.
        • Panagiotidou A.
        • Singh J.
        • et al.
        Mechanism of corrosion in large diameter head metal-on-metal total hip arthroplasty: A retireval analysis of 161 components.
        2013
        • Singh G.
        • Meyer H.
        • Ruetschi M.
        • et al.
        Large‐diameter metal‐on‐metal total hip arthroplasties: A page in orthopedic history?.
        J Biomed Mater Res A. 2013; 101: 3320
        • Elkins J.M.
        • Callaghan J.J.
        • Brown T.D.
        Stability and trunnion wear potential in large-diameter metal-on-metal total hips: A finite element analysis.
        Clin Orthop Relat Res. 2014; 472: 529
        • Munro J.T.
        • Masri B.A.
        • Duncan C.P.
        • et al.
        High complication rate after revision of large-head metal-on-metal total hip arthroplasty.
        Clin Orthop Relat Res. 2014; 472: 523
        • Beaulé P.E.
        • Kim P.R.
        • Hamdi A.
        • et al.
        A prospective metal ion study of large-head metal-on-metal bearing: a matched-pair analysis of hip resurfacing versus total hip replacement.
        Orthop Clin North Am. 2011; 42: 251
        • Craig P.
        • Bancroft G.
        • Burton A.
        • et al.
        Raised levels of metal ions in the blood in patients who have undergone uncemented metal-on-polyethylene Trident-Accolade total hip replacement.
        Bone Joint J. 2014; 96-B: 43
        • Nganbe M.
        • Khan U.
        • Louati H.
        • et al.
        In vitro assessment of strength, fatigue durability, and disassembly of Ti6Al4V and CoCrMo necks in modular total hip replacements.
        J Biomed Mater Res B Appl Biomater. 2011; 97: 132
        • Grupp T.M.
        • Weik T.
        • Bloemer W.
        • et al.
        Modular titanium alloy neck adapter failures in hip replacement – failure mode analysis and influence of implant material.
        BMC Musculoskelet Disord. 2010; 11: 3