Abstract
Background
Although alcohol is a leading risk factor for osteonecrosis of the femoral head (ONFH)
and its prevalence reportedly ranges from 20% to 45%, there are no unified classification
criteria for this subpopulation. In 2015, Association Research Circulation Osseous
decided to develop classification criteria for alcohol-associated ONFH.
Methods
In June of 2017, Association Research Circulation Osseous formed a task force to conduct
a Delphi survey. The task force invited 28 experts in osteonecrosis/bone circulation
from 8 countries. Each round of the Delphi survey included questionnaires, analysis
of replies, and feedback reports to the panel. After 3 rounds of the survey, consensus
was reached on the classification criteria. The response rates for the 3 Delphi rounds
were 100% (round 1), 96% (round 2), and 100% (round 3).
Results
The consensus on the classification criteria of alcohol-associated ONFH included the
following: (1) patients should have a history of alcohol intake >400 mL/wk (320 g/wk,
any type of alcoholic beverage) of pure ethanol for more than 6 months; (2) ONFH should
be diagnosed within 1 year after alcohol intake of this dose; and (3) patients should
not have other risk factor(s).
Conclusion
ARCO-established classification criteria to standardize clinical studies concerning
AA-ONFH.
Keywords
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Article info
Publication history
Published online: September 21, 2018
Accepted:
September 10,
2018
Received in revised form:
August 28,
2018
Received:
July 18,
2018
Footnotes
Byung-Ho Yoon and Lynne C. Jones equally contributed to this work and should be considered co-first author.
No author associated with this paper has disclosed any potential or pertinent conflicts which may be perceived to have impending conflict with this work. For full disclosure statements refer to https://doi.org/10.1016/j.arth.2018.09.006.
Source of Funding: No external funding was received in support of this work and ARCO.
Identification
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