Abstract
Background
The purpose of this study is to evaluate the 5-factor modified frailty index (mFI-5)
as a predictor of postoperative complications, readmission, and mortality in patients
undergoing revision hip and knee arthroplasty.
Methods
A retrospective analysis of the American College of Surgeon’s National Surgical Quality
Improvement Program’s database for patients undergoing revision total hip arthroplasty
(rTHA) and revision total knee arthroplasty (rTKA) between the years 2005 and 2016
was conducted. The 5-factor score, which includes presence of comorbid diabetes, hypertension,
congestive heart failure, chronic obstructive pulmonary disease, and functional status,
was calculated for each patient. Multivariate logistic regression models were used
to assess the relationship between the mFI-5 and postoperative complications while
controlling for demographic variables.
Results
In total, 13,948 patients undergoing rTHA and 16,304 patients undergoing rTKA were
identified. The mFI-5 was a strong predictor of serious medical complications (cardiac
arrest, myocardial infarction, septic shock, pulmonary embolism, postoperative dialysis,
reintubation, and prolonged ventilator requirement), discharge to a facility, total
length of stay, readmission, and mortality (P ≤ .007).
Conclusion
The mFI-5 predicts serious medical complications, increased length of stay, discharge
to a facility, hospital readmission, and mortality in patients undergoing rTHA and
rTKA. All the variables within the mFI-5 are easily obtained through the patient history,
allowing for a practical clinical tool that hospitals and physicians can use to identify
at-risk patients, educate and engage patients and their families in a shared decision-making
conversation, and guide perioperative care in order to optimize patient outcomes.
Level of Evidence
III.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic and PersonalCorporate R&D ProfessionalsOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to The Journal of ArthroplastyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Discriminative ability for adverse outcomes after surgical management of hip fractures.J Orthop Trauma. 2018; 32: 231-237https://doi.org/10.1097/BOT.0000000000001140
- A comparison of the Charlson and Elixhauser comorbidity measures to predict inpatient mortality after proximal humerus fracture.J Orthop Trauma. 2015; 29: 488-493https://doi.org/10.1097/BOT.0000000000000380
- A preoperative scale for determining surgical readmission risk after total hip replacement.JAMA Surg. 2016; 151: 701-709https://doi.org/10.1001/jamasurg.2016.0020
- A standard procedure for creating a frailty index.BMC Geriatr. 2008; 8: 24https://doi.org/10.1186/1471-2318-8-24
- Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian study of health and aging.J Gerontol A Biol Sci Med Sci. 2004; 59: 1310-1317
- Accumulating deficits model of frailty and postoperative mortality and morbidity: its application to a national database.J Surg Res. 2013; 183: 104-110https://doi.org/10.1016/j.jss.2013.01.021
- New 5-factor modified frailty index using American College of Surgeons NSQIP data.J Am Coll Surg. 2018; 226: 173-178https://doi.org/10.1016/j.jamcollsurg.2017.11.005
- Simplified frailty index as a predictor of adverse outcomes in total hip and knee arthroplasty.J Arthroplasty. 2016; 31: 2389-2394https://doi.org/10.1016/j.arth.2016.04.020
- Modified frailty index is an effective risk assessment tool in primary total knee arthroplasty.J Arthroplasty. 2017; 32: S177-S182https://doi.org/10.1016/j.arth.2017.03.046
- Modified frailty index is an effective risk assessment tool in primary total hip arthroplasty.J Arthroplasty. 2017; 32: 2963-2968https://doi.org/10.1016/j.arth.2017.04.056
- New 5-factor modified frailty index predicts morbidity and mortality in primary hip and knee arthroplasty.J Arthroplasty. 2019; 34: 140-144https://doi.org/10.1016/j.arth.2018.09.040
- Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.Ann Surg. 2004; 240: 205-213https://doi.org/10.1097/01.sla.0000133083.54934.ae
- Proposed classification of complications of surgery with examples of utility in cholecystectomy.Surgery. 1992; 111: 518-526
- Use of a 5-item modified frailty index for risk stratification in patients undergoing surgical management of distal radius fractures.J Hand Surg Am. 2018; 43: 701-709https://doi.org/10.1016/j.jhsa.2018.05.029
- New 5-factor modified frailty index predicts morbidity and mortality in geriatric hip fractures.J Orthop Trauma. 2019; (Epub ahead of print)https://doi.org/10.1097/BOT.0000000000001455
- Discriminative ability of commonly used indices to predict adverse outcomes after poster lumbar fusion: a comparison of demographics, ASA, the modified Charlson Comorbidity Index, and the modified Frailty Index.Spine J. 2018; 18: 44-52https://doi.org/10.1016/j.spinee.2017.05.028
- The economic impact of periprosthetic infections following total knee arthroplasty at a specialized tertiary-care center.J Arthroplasty. 2014; 29: 929-932https://doi.org/10.1016/j.arth.2013.09.017
- Cost analysis of total joint arthroplasty readmissions in a bundled payment care improvement initiative.J Arthroplasty. 2016; 31: 1862-1865https://doi.org/10.1016/j.arth.2016.02.029
- The “bundle busters”: incidence and costs of postacute complications following total joint arthroplasty.J Arthroplasty. 2018; 33: 2734-2739https://doi.org/10.1016/j.arth.2018.05.015
- Which clinical and patient factors influence the national economic burden of hospital readmissions after total joint arthroplasty?.Clin Orthop Relat Res. 2017; 475: 2926-2937https://doi.org/10.1007/s11999-017-5244-6
- 2,573 hospitals will face readmission penalties this year. Is yours one of them?.([accessed 11.12.18])
Article Info
Publication History
Published online: March 06, 2019
Accepted:
February 27,
2019
Received in revised form:
February 13,
2019
Received:
December 17,
2018
Footnotes
One or more of the authors of this paper have disclosed potential or pertinent conflicts of interest, which may include receipt of payment, either direct or indirect, institutional support, or association with an entity in the biomedical field which may be perceived to have potential conflict of interest with this work. For full disclosure statements refer to https://doi.org/10.1016/j.arth.2019.02.060.
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.

