- •Medicare and weighted private insurance claims data were combined to create a large, nationally representative cohort of THA and TKA patients aged 18 to 75 years.
- •Opioid prescription refill occurs in most patients after TKA and is common after THA.
- •Larger initial opioid prescription size after TKA and THA is associated with a small but clinically insignificant decrease in opioid refills in the 30 days after surgery.
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One or more of the authors of this paper have disclosed potential or pertinent conflicts of interest, which may include receipt of payment, either direct or indirect, institution support, or association with an entity in the biomedical field which may be perceived to have potential conflict of interest with this work. For full disclosure statements refer to https://doi.org/10.1016/j.arth.2022.10.038.
Ethical review committee statement: This study received “not regulated” status by our institutional review board on 8/13/2016 (HUM00118524).
Funding: JW, MB, and CB receive funding from the Michigan Department of Health and Human Services and the National Institute on Drug Abuse ( R01DA042859 ). Additional funding from the University of Michigan Precision Health Initiative.
Conflict of interest statement: MB reports past consultation with Axial Health care and Alosa Health not related to this work. CB is a consultant for Heron Therapeutics, Vertex Pharmaceuticals, Alosa Health, and the Benter Foundation, not related to this work. He also provides expert testimony. BH receives partial salary support from Blue Cross Blue Shield of Michigan for work on the Michigan Arthoplasty Registry Collaborative Quality Initiative and serves as a committee member for data committee of the AAOS American Joint Replacement Registry. No funder or sponsor had any role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication. HMH had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.